Endocrine Abstracts

A 41 year-old gentleman, known case of type 2 diabetes, presented to the emergency department after a witnessed episode of jaw clenching followed by unresponsiveness. The patient was amnesic to the event. He was noted to have a lateral tongue bite. He also reported a similar episode 8 months previously. Initial blood investigations including a random blood glucose were normal. A sulphonylurea induced hypoglycaemia was excluded. Brain imaging by means of a Computed Tomography (...

A 41 year old female, followed up closely by cardiology in view of grown up congenital heart disease secondary to tricuspid atresia, pulmonary stenosis and atrial septal defect in infacy, and brittle paroxysmal atrial fibrillation (AF) was noted to be progressively lethargic and anorexic. She also developed bilateral lower limb oedema and was admitted for further investigation of decompensated congestive heart failure (CHF). Overt thyrotoxicosis was found on investigation. Sin...

A 52 year-old female, newly diagnosed with Type 2 Diabetes during pre-operative assessment for cholecystectomy, was referred to Diabetes clinic. An initial trial of metformin was discontinued in view of intolerable gastrointestinal side effects and the patient was started on low dose gliclazide. The patient’s main concern was her struggle to lose weight despite lifestyle measures, a seemingly common issue faced by patients with diabetes on sulphonylureas. On further exami...